Bioactive phenolic amides from Celtis africana.

نویسندگان

  • Areej Mohammad Al-Taweel
  • Shagufta Perveen
  • Azza Muhammed El-Shafae
  • Ghada Ahmed Fawzy
  • Abdul Malik
  • Nighat Afza
  • Lubna Iqbal
  • Mehreen Latif
چکیده

Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1-3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity.

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عنوان ژورنال:
  • Molecules

دوره 17 3  شماره 

صفحات  -

تاریخ انتشار 2012